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Gene : ACACB Homo sapiens

Name  ? acetyl-CoA carboxylase beta Cytological Location  12q24.11
Brief Description  acetyl-CoA carboxylase beta
description  Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_001093,
  • U89344,
  • acetyl-Coenzyme A carboxylase beta,
  • ACC2,
  • HACC275,
  • uc001tob.4,
  • HACC275,
  • acetyl-CoA carboxylase 2,
  • ACACB,
  • ACCB,
  • ACCB,
  • HGNC:85,
  • ACC2,
  • OTTHUMG00000169250
  • identifiers:
  • 32,
  • ENSG00000076555,
  • ACACB

Genome feature

Region: gene ? Length: 155561  
Location: 12:109112666-109268226 Cyto location: 12q24.11


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Disease

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Other

558 SN Ps

5 Cross References

18 Data Sets

9 Homologues

0 Located Features

90 Rna Seq Results