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Gene : APBB2 Homo sapiens

Name  ? amyloid beta precursor protein binding family B member 2 Cytological Location  4p14-p13
Brief Description  amyloid beta precursor protein binding family B member 2
description  The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  • synonyms:
  • amyloid beta (A4) precursor protein-binding, family B, member 2,
  • HGNC:582,
  • FE65L,
  • uc003gvm.4,
  • NM_173075,
  • APBB2,
  • FE65L1,
  • OTTHUMG00000160416,
  • FE65L,
  • Fe65-like,
  • MGC35575,
  • U62325,
  • FE65L1
  • identifiers:
  • 323,
  • ENSG00000163697,
  • APBB2

Genome feature

Region: gene ? Length: 406688  
Location: 4:40810027-41216714 reverse strand Cyto location: 4p14-p13


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

683 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

90 Rna Seq Results