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Gene : HTR2A Homo sapiens

Name  ? 5-hydroxytryptamine receptor 2A Cytological Location  13q14.2
Brief Description  5-hydroxytryptamine receptor 2A
description  This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • synonyms:
  • X57830,
  • NM_000621,
  • 5-HT2A,
  • 5-HT2A,
  • HTR2,
  • HTR2,
  • uc010acr.5,
  • 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled,
  • HTR2A,
  • HGNC:5293,
  • 5-hydroxytryptamine (serotonin) receptor 2A,
  • OTTHUMG00000016881
  • identifiers:
  • 3356,
  • ENSG00000102468,
  • HTR2A

Genome feature

Region: gene ? Length: 65535  
Location: 13:46831542-46897076 reverse strand Cyto location: 13q14.2


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

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SNPs

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Disease

5 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

2011 SN Ps

5 Cross References

19 Data Sets

39 Homologues

0 Located Features

90 Rna Seq Results