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Gene : IBSP Homo sapiens

Name  ? integrin binding sialoprotein Cytological Location  4q22.1
Brief Description  integrin binding sialoprotein
description  The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008]
  • synonyms:
  • BSP-II,
  • uc003hqx.5,
  • OTTHUMG00000130600,
  • SP-II,
  • bone sialoprotein,
  • HGNC:5341,
  • NM_004967,
  • SP-II,
  • BSP-II,
  • BSP,
  • IBSP,
  • bone sialoprotein II,
  • BSP,
  • BNSP
  • identifiers:
  • 3381,
  • ENSG00000029559,
  • IBSP

Genome feature

Region: gene ? Length: 12900  
Location: 4:87799550-87812449 Cyto location: 4q22.1


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Function

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Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

263 SN Ps

4 Cross References

14 Data Sets

2 Homologues

0 Located Features

90 Rna Seq Results