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Gene : MALRD1 Homo sapiens

Name  ? MAM and LDL receptor class A domain containing 1 Cytological Location  10p12.31
Brief Description  MAM and LDL receptor class A domain containing 1
description  This gene encodes a conserved protein that features multiple MAM (meprin-A5-protein tyrosine phosphatase mu) and LDLR A2 (low density lipoprotein receptor A2) domains. Expression of this gene is enriched in the small intestine and is upregulated during differentiation of a human cell line that exhibits properties of intestinal epithelial cells. The encoded protein has been shown to modulate production of FGF19 in a human intestinal cell line and may regulate bile acid metabolism in the liver. A synergistic interaction between an allele of this gene and the APOE E4 allele is associated with an elevated risk of Alzheimer's disease in human patients. [provided by RefSeq, Jul 2017]
  • synonyms:
  • HGNC:24331,
  • chromosome 10 open reading frame 112,
  • Diet1,
  • bA265G8.2,
  • bA265G8.2,
  • C10orf112,
  • OTTHUMG00000017779,
  • MALRD1,
  • KC843478,
  • NM_001142308,
  • DIET1,
  • C10orf112
  • identifiers:
  • 340895,
  • ENSG00000204740,
  • MALRD1

Genome feature

Region: gene ? Length: 687548  
Location: 10:19046931-19734478 Cyto location: 10p12.31


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Proteins

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SNPs

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Disease

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Expression

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0 Pathways

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4 Cross References

14 Data Sets

11 Homologues

0 Located Features

90 Rna Seq Results