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Gene : JAK1 Homo sapiens

Name  ? Janus kinase 1 Cytological Location  1p31.3
Brief Description  Janus kinase 1
description  This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
  • synonyms:
  • uc001dbu.2,
  • HGNC:6190,
  • NM_002227,
  • OTTHUMG00000009310,
  • M64174,
  • JTK3,
  • JAK1B,
  • JAK1B,
  • JAK1,
  • JTK3,
  • JAK1A,
  • JAK1A
  • identifiers:
  • 3716,
  • ENSG00000162434,
  • JAK1

Genome feature

Region: gene ? Length: 234524  
Location: 1:64833223-65067746 reverse strand Cyto location: 1p31.3

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Gene --> GO terms.

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



824 SN Ps

5 Cross References

18 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results