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Gene : KCNQ3 Homo sapiens

Name  ? potassium voltage-gated channel subfamily Q member 3 Cytological Location  8q24.22
Brief Description  potassium voltage-gated channel subfamily Q member 3
description  This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]
  • synonyms:
  • BFNC2,
  • uc003ytj.4,
  • EBN2,
  • OTTHUMG00000137472,
  • AB208890,
  • KCNQ3,
  • potassium channel, voltage gated KQT-like subfamily Q, member 3,
  • HGNC:6297,
  • potassium voltage-gated channel, KQT-like subfamily, member 3,
  • EBN2,
  • NM_004519,
  • KV7.3,
  • Kv7.3
  • identifiers:
  • 3786,
  • ENSG00000184156,
  • KCNQ3

Genome feature

Region: gene ? Length: 359900  
Location: 8:132120858-132480757 reverse strand Cyto location: 8q24.22

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1 Diseases

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206 SN Ps

5 Cross References

17 Data Sets

37 Homologues

0 Located Features

90 Rna Seq Results