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Gene : KPNA1 Homo sapiens

Name  ? karyopherin subunit alpha 1 Cytological Location  3q21.1
Brief Description  karyopherin subunit alpha 1
description  The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
  • synonyms:
  • importin alpha 5,
  • IPOA5,
  • karyopherin alpha 1 (importin alpha 5),
  • KPNA1,
  • RCH2,
  • NPI-1,
  • OTTHUMG00000159487,
  • RCH2,
  • NPI-1,
  • IPOA5,
  • SRP1,
  • uc003efe.3,
  • SRP1,
  • NM_002264,
  • HGNC:6394,
  • S75295,
  • karyopherin alpha 1
  • identifiers:
  • 3836,
  • ENSG00000114030,
  • KPNA1

Genome feature

Region: gene ? Length: 93039  
Location: 3:122421901-122514939 reverse strand Cyto location: 3q21.1

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Gene -> HPO annotation (Human Phenotype Ontology)

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> GO terms.



965 SN Ps

5 Cross References

16 Data Sets

14 Homologues

0 Located Features

90 Rna Seq Results