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Gene : GPR153 Homo sapiens

Name  ? G protein-coupled receptor 153 Cytological Location  1p36.31
Brief Description  G protein-coupled receptor 153
description  This gene encodes an integral membrane protein that belongs to the Class A rhodopsin superfamily of G protein coupled receptors. The encoded protein is expressed primarily in the central nervous system. A knockdown of the orthologous gene in rat is associated with a significant reduction in food intake and impaired decision making ability. Mutations in this gene are associated with schizophrenia, autism, and other neuropsychiatric disorders. The expression of this gene is activated by the glioma-associated oncogene homolog 1 transcription factor which, in turn, is activated by sonic hedgehog in normal and tumorigenic cells. [provided by RefSeq, Feb 2017]
  • synonyms:
  • uc001amp.2,
  • NM_207370,
  • GPR153,
  • PGR1,
  • PGR1,
  • AY255529,
  • OTTHUMG00000001272,
  • HGNC:23618
  • identifiers:
  • 387509,
  • ENSG00000158292,
  • GPR153

Genome feature

Region: gene ? Length: 13630  
Location: 1:6247346-6260975 reverse strand Cyto location: 1p36.31

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

253 SN Ps

4 Cross References

14 Data Sets

3 Homologues

0 Located Features

90 Rna Seq Results