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Gene : AFF3 Homo sapiens

Name  ? AF4/FMR2 family member 3 Cytological Location  2q11.2
Brief Description  AF4/FMR2 family member 3
description  This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • MLLT2-like,
  • MLLT2-like,
  • lymphoid nuclear protein related to AF4,
  • LAF4,
  • uc002tah.2,
  • LAF4,
  • U34360,
  • AF4/FMR2 family, member 3,
  • AFF3,
  • NM_002285,
  • OTTHUMG00000153011,
  • HGNC:6473
  • identifiers:
  • 3899,
  • ENSG00000144218,
  • AFF3

Genome feature

Region: gene ? Length: 596723  
Location: 2:99545861-100142583 reverse strand Cyto location: 2q11.2


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

2011 SN Ps

5 Cross References

17 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results