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Gene : MCM3 Homo sapiens

Name  ? minichromosome maintenance complex component 3 Cytological Location  6p12.2
Brief Description  minichromosome maintenance complex component 3
description  The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2018]
  • synonyms:
  • HGNC:6945,
  • NM_001270472,
  • X62153,
  • P1-MCM3,
  • uc063ozz.1,
  • HCC5,
  • RLFB,
  • minichromosome maintenance deficient (S. cerevisiae) 3,
  • P1.h,
  • MCM3 minichromosome maintenance deficient 3 (S. cerevisiae),
  • MCM3,
  • OTTHUMG00000014844
  • identifiers:
  • 4172,
  • ENSG00000112118,
  • MCM3

Genome feature

Region: gene ? Length: 20868  
Location: 6:52264014-52284881 reverse strand Cyto location: 6p12.2

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0 Diseases

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298 SN Ps

5 Cross References

17 Data Sets

14 Homologues

0 Located Features

90 Rna Seq Results