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Gene : MFGE8 Homo sapiens

Name  ? milk fat globule-EGF factor 8 protein Cytological Location  15q26.1
Brief Description  milk fat globule-EGF factor 8 protein
description  This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
  • synonyms:
  • HsT19888,
  • MFGE8,
  • SPAG10,
  • HGNC:7036,
  • BA46,
  • SED1,
  • hP47,
  • BA46,
  • SED1,
  • lactadherin,
  • HsT19888,
  • OTTHUMG00000148682,
  • MFG-E8,
  • U58516,
  • HMFG,
  • hP47,
  • sperm surface protein hP47,
  • OAcGD3S,
  • EDIL1,
  • SPAG10,
  • uc002bng.5,
  • MFG-E8,
  • sperm associated antigen 10,
  • NM_005928,
  • MFGM,
  • EDIL1,
  • OAcGD3S
  • identifiers:
  • 4240,
  • ENSG00000140545,
  • MFGE8

Genome feature

Region: gene ? Length: 14787  
Location: 15:88898683-88913469 reverse strand Cyto location: 15q26.1

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0 Diseases

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2011 SN Ps

5 Cross References

16 Data Sets

8 Homologues

0 Located Features

90 Rna Seq Results