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Gene : MGAT5 Homo sapiens

Name  ? alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase Cytological Location  2q21.2-q21.3
Brief Description  mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
description  The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. [provided by RefSeq, Oct 2011]
  • synonyms:
  • MGAT5A,
  • D17716,
  • OTTHUMG00000131681,
  • uc061nyh.1,
  • NM_002410,
  • GNT-V,
  • alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A,
  • GNT-V,
  • MGAT5A,
  • GNT-VA,
  • MGAT5,
  • mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase,
  • HGNC:7049
  • identifiers:
  • 4249,
  • ENSG00000152127,
  • MGAT5

Genome feature

Region: gene ? Length: 334700  
Location: 2:134119922-134454621 Cyto location: 2q21.2-q21.3


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33 SN Ps

5 Cross References

17 Data Sets

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90 Rna Seq Results