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Gene : AFDN Homo sapiens

Name  ? afadin, adherens junction formation factor Cytological Location  6q27
Brief Description  afadin, adherens junction formation factor
description  This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011]
  • synonyms:
  • AF6,
  • MLL-AF6,
  • NM_005936,
  • AF6,
  • MLLT4,
  • uc063sxr.1,
  • AF-6,
  • HGNC:7137,
  • AB011399,
  • l-afadin,
  • MLLT4,
  • AFDN,
  • OTTHUMG00000016031,
  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4
  • identifiers:
  • 4301,
  • ENSG00000130396,
  • AFDN

Genome feature

Region: gene ? Length: 145152  
Location: 6:167826872-167972023 Cyto location: 6q27


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Disease

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Expression

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2011 SN Ps

5 Cross References

18 Data Sets

5 Homologues

0 Located Features

90 Rna Seq Results