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Gene : PPP1R12B Homo sapiens

Name  ? protein phosphatase 1 regulatory subunit 12B Cytological Location  1q32.1
Brief Description  protein phosphatase 1 regulatory subunit 12B
description  Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome. [provided by RefSeq, Oct 2011]
  • synonyms:
  • PPP1R12B,
  • MGC87886,
  • HGNC:7619,
  • MYPT2,
  • PP1bp55,
  • myosin phosphatase regulatory subunit,
  • OTTHUMG00000041393,
  • myosin phosphatase, target subunit 2,
  • MGC131980,
  • uc001gya.3,
  • protein phosphatase 1, regulatory (inhibitor) subunit 12B,
  • NM_032105,
  • AB003062,
  • PP1bp55,
  • MYPT2,
  • protein phosphatase 1, regulatory subunit 12B
  • identifiers:
  • 4660,
  • ENSG00000077157,
  • PPP1R12B

Genome feature

Region: gene ? Length: 239868  
Location: 1:202348702-202588569 Cyto location: 1q32.1

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0 Diseases

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311 SN Ps

5 Cross References

18 Data Sets

7 Homologues

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90 Rna Seq Results