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Gene : NPM1 Homo sapiens

Name  ? nucleophosmin 1 Cytological Location  5q35.1
Brief Description  nucleophosmin 1
description  The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]
  • synonyms:
  • NM_002520,
  • NPM,
  • OTTHUMG00000130465,
  • B23,
  • nucleophosmin,
  • nucleophosmin (nucleolar phosphoprotein B23, numatrin),
  • uc032vtc.2,
  • B23,
  • nucleophosmin/nucleoplasmin family, member 1,
  • numatrin,
  • M26697,
  • nucleolar phosphoprotein B23,
  • NPM,
  • HGNC:7910,
  • NPM1
  • identifiers:
  • 4869,
  • ENSG00000181163,
  • NPM1

Genome feature

Region: gene ? Length: 23769  
Location: 5:171387116-171410884 Cyto location: 5q35.1

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Gene --> GO terms.

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Gene --> Proteins.


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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



43 SN Ps

5 Cross References

18 Data Sets

10 Homologues

0 Located Features

90 Rna Seq Results