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Gene : NRGN Homo sapiens

Name  ? neurogranin Cytological Location  11q24.2
Brief Description  neurogranin
description  Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008]
  • synonyms:
  • X99075,
  • OTTHUMG00000165928,
  • NM_006176,
  • X99076,
  • NRGN,
  • neurogranin (protein kinase C substrate, RC3),
  • hng,
  • RC3,
  • RC3,
  • HGNC:8000,
  • uc001qaq.3
  • identifiers:
  • 4900,
  • ENSG00000154146,
  • NRGN

Genome feature

Region: gene ? Length: 7274  
Location: 11:124739933-124747206 Cyto location: 11q24.2

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



106 SN Ps

5 Cross References

15 Data Sets

0 Homologues

0 Located Features

90 Rna Seq Results