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Gene : PCK1 Homo sapiens

Name  ? phosphoenolpyruvate carboxykinase 1 Cytological Location  20q13.31
Brief Description  phosphoenolpyruvate carboxykinase 1
description  This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq, Jul 2008]
  • synonyms:
  • PEPCK1,
  • PEPCK-C,
  • phosphoenolpyruvate carboxykinase 1 (soluble),
  • PCK1,
  • NM_002591,
  • OTTHUMG00000032825,
  • PEPCK-C,
  • PCKDC,
  • PEPCKC,
  • HGNC:8724,
  • uc002xyn.5
  • identifiers:
  • 5105,
  • ENSG00000124253,
  • PCK1

Genome feature

Region: gene ? Length: 5381  
Location: 20:57561081-57566461 Cyto location: 20q13.31


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Disease

1 Diseases

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82 SN Ps

5 Cross References

20 Data Sets

9 Homologues

0 Located Features

90 Rna Seq Results