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Gene : ANGPTL4 Homo sapiens

Name  ? angiopoietin like 4 Cytological Location  19p13.2
Brief Description  angiopoietin like 4
description  This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013]
  • synonyms:
  • hepatic fibrinogen/angiopoietin-related protein,
  • UNQ171,
  • AF202636,
  • PGAR,
  • FIAF,
  • peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein,
  • PPARG angiopoietin related protein,
  • NL2,
  • pp1158,
  • PGAR,
  • hepatic angiopoietin-related protein,
  • ARP4,
  • HFARP,
  • FIAF,
  • HARP,
  • NM_139314,
  • angiopoietin-related protein 4,
  • ARP4,
  • TGQTL,
  • NL2,
  • angiopoietin-like 4,
  • fasting-induced adipose factor,
  • ANGPTL4,
  • HGNC:16039,
  • uc002mjq.3,
  • pp1158,
  • HFARP,
  • OTTHUMG00000182273
  • identifiers:
  • 51129,
  • ENSG00000167772,
  • ANGPTL4

Genome feature

Region: gene ? Length: 10249  
Location: 19:8364127-8374375 Cyto location: 19p13.2


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Disease

1 Diseases

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166 SN Ps

5 Cross References

20 Data Sets

27 Homologues

0 Located Features

90 Rna Seq Results