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Gene : ABI3 Homo sapiens

Name  ? ABI family member 3 Cytological Location  17q21.32
Brief Description  ABI family member 3
description  This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  • synonyms:
  • ABI3,
  • SSH3BP3,
  • uc002iop.1,
  • AB037886,
  • OTTHUMG00000161306,
  • NESH,
  • SSH3BP3,
  • NESH,
  • NM_016428,
  • ABI family, member 3,
  • HGNC:29859
  • identifiers:
  • 51225,
  • ENSG00000108798,
  • ABI3

Genome feature

Region: gene ? Length: 12999  
Location: 17:49210227-49223225 Cyto location: 17q21.32


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

39 SN Ps

5 Cross References

15 Data Sets

5 Homologues

0 Located Features

90 Rna Seq Results