help  | about  | cite  | software

Gene : PDE4C Homo sapiens

Name  ? phosphodiesterase 4C Cytological Location  19p13.11
Brief Description  phosphodiesterase 4C
description  The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
  • synonyms:
  • DPDE1,
  • PDE4C,
  • HGNC:8782,
  • phosphodiesterase E1 dunce homolog (Drosophila),
  • DPDE1,
  • NM_000923,
  • OTTHUMG00000183353,
  • phosphodiesterase 4C, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E1),
  • phosphodiesterase 4C, cAMP-specific,
  • uc002nil.4,
  • PDE21
  • identifiers:
  • 5143,
  • ENSG00000105650,
  • PDE4C

Genome feature

Region: gene ? Length: 40240  
Location: 19:18207961-18248200 reverse strand Cyto location: 19p13.11

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



933 SN Ps

5 Cross References

15 Data Sets

27 Homologues

0 Located Features

90 Rna Seq Results