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Gene : ASB2 Homo sapiens

Name  ? ankyrin repeat and SOCS box containing 2 Cytological Location  14q32.12
Brief Description  ankyrin repeat and SOCS box containing 2
description  This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
  • synonyms:
  • NM_001202429,
  • ankyrin repeat and SOCS box-containing 2,
  • ASB-2,
  • ASB-2,
  • AF159164,
  • HGNC:16012,
  • ASB2,
  • OTTHUMG00000171298,
  • uc001ycc.3
  • identifiers:
  • 51676,
  • ENSG00000100628,
  • ASB2

Genome feature

Region: gene ? Length: 42587  
Location: 14:93934153-93976739 reverse strand Cyto location: 14q32.12


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> GO terms.

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

46 SN Ps

5 Cross References

13 Data Sets

16 Homologues

0 Located Features

90 Rna Seq Results