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Gene : PFKFB1 Homo sapiens

Name  ? 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Cytological Location  Xp11.21
Brief Description  6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
description  This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]
  • synonyms:
  • NM_001271804,
  • OTTHUMG00000021643,
  • PFRX,
  • PFRX,
  • F6PK,
  • HGNC:8872,
  • HL2K,
  • uc004dty.3,
  • PFKFB1
  • identifiers:
  • 5207,
  • ENSG00000158571,
  • PFKFB1

Genome feature

Region: gene ? Length: 66919  
Location: X:54933134-55000052 reverse strand Cyto location: Xp11.21


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66 SN Ps

5 Cross References

16 Data Sets

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90 Rna Seq Results