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Gene : RNF216 Homo sapiens

Name  ? ring finger protein 216 Cytological Location  7p22.1
Brief Description  ring finger protein 216
description  This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CAHH,
  • NM_207111,
  • UBCE7IP1,
  • ZIN,
  • RNF216,
  • UBCE7IP1,
  • TRIAD3,
  • AY062174,
  • ZIN,
  • uc003sox.3,
  • TRIAD3,
  • OTTHUMG00000155500,
  • U7I1,
  • HGNC:21698
  • identifiers:
  • 54476,
  • ENSG00000011275,
  • RNF216

Genome feature

Region: gene ? Length: 161690  
Location: 7:5620041-5781730 reverse strand Cyto location: 7p22.1

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1 Diseases

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147 SN Ps

5 Cross References

19 Data Sets

5 Homologues

0 Located Features

90 Rna Seq Results