help  | about  | cite  | software

Gene : MAGEL2 Homo sapiens

Name  ? MAGE family member L2 Cytological Location  15q11.2
Brief Description  MAGE family member L2
description  Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS. [provided by RefSeq, Oct 2010]
  • synonyms:
  • PWLS,
  • MAGE-like 2,
  • OTTHUMG00000167582,
  • MAGEL2,
  • NDNL1,
  • nM15,
  • HGNC:6814,
  • NM_019066,
  • NDNL1,
  • SHFYNG,
  • AJ243531,
  • uc001ywj.5,
  • nM15,
  • melanoma antigen family L2
  • identifiers:
  • 54551,
  • ENSG00000254585,
  • MAGEL2

Genome feature

Region: gene ? Length: 4298  
Location: 15:23643549-23647846 reverse strand Cyto location: 15q11.2


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

0 SN Ps

5 Cross References

15 Data Sets

40 Homologues

0 Located Features

90 Rna Seq Results