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Gene : PPP1CA Homo sapiens

Name  ? protein phosphatase 1 catalytic subunit alpha Cytological Location  11q13.2
Brief Description  protein phosphatase 1 catalytic subunit alpha
description  The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc001okw.2,
  • PP1alpha,
  • OTTHUMG00000167671,
  • protein phosphatase 1, catalytic subunit, alpha isozyme,
  • PPP1A,
  • PP1alpha,
  • PPP1CA,
  • NM_002708,
  • HGNC:9281,
  • PP1A,
  • PP-1A,
  • PP-1A,
  • protein phosphatase 1, catalytic subunit, alpha isoform,
  • PPP1A,
  • PP1A
  • identifiers:
  • 5499,
  • ENSG00000172531,
  • PPP1CA

Genome feature

Region: gene ? Length: 3725  
Location: 11:67398181-67401905 reverse strand Cyto location: 11q13.2

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0 Diseases

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21 SN Ps

5 Cross References

17 Data Sets

36 Homologues

0 Located Features

90 Rna Seq Results