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Gene : ARMC4 Homo sapiens

Name  ? armadillo repeat containing 4 Cytological Location  10p12.1
Brief Description  armadillo repeat containing 4
description  The protein encoded by this gene contains ten Armadillo repeat motifs (ARMs) and one HEAT repeat, and is thought to be involved in ciliary and flagellar movement. This protein has been shown to localize to the ciliary axonemes and at the ciliary base of respiratory cells. Studies indicate that mutations in this gene cause partial outer dynein arm (ODA) defects in respiratory cilia. The cilia of cells with mutations in this gene displayed either reduced ciliary beat frequency and amplitude, or, complete immotility. Some individuals with primary ciliary dyskensia (PCD) have been shown to have mutations in this gene. PCD is characterized by chronic airway disease and left/right body asymmetry defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
  • synonyms:
  • DKFZP434P1735,
  • ARMC4,
  • NM_018076,
  • CILD23,
  • CILD23,
  • AL136859,
  • OTTHUMG00000017867,
  • uc001itz.3,
  • HGNC:25583,
  • FLJ10817,
  • FLJ10376
  • identifiers:
  • 55130,
  • ENSG00000169126,
  • ARMC4

Genome feature

Region: gene ? Length: 187337  
Location: 10:27812164-27999500 reverse strand Cyto location: 10p12.1


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Mouse Gene --> Allele [Phenotype]

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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Mouse Gene --> Allele [Phenotype]

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0 Pathways

123 SN Ps

4 Cross References

18 Data Sets

4 Homologues

0 Located Features

90 Rna Seq Results