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Gene : ASXL2 Homo sapiens

Name  ? ASXL transcriptional regulator 2 Cytological Location  2p23.3
Brief Description  additional sex combs like 2, transcriptional regulator
description  This gene encodes a member of a family of epigenetic regulators that bind various histone-modifying enzymes and are involved in the assembly of transcription factors at specific genomic loci. Naturally occurring mutations in this gene are associated with cancer in several tissue types (breast, bladder, pancreas, ovary, prostate, and blood). This gene plays an important role in neurodevelopment, cardiac function, adipogenesis, and osteoclastogenesis. [provided by RefSeq, Feb 2017]
  • synonyms:
  • NM_018263,
  • SHAPNS,
  • additional sex combs like 2, transcriptional regulator,
  • KIAA1685,
  • uc061hgj.1,
  • ASXL2,
  • ASXH2,
  • FLJ10898,
  • OTTHUMG00000152176,
  • HGNC:23805,
  • ASXH2,
  • additional sex combs like 2 (Drosophila)
  • identifiers:
  • 55252,
  • ENSG00000143970,
  • ASXL2

Genome feature

Region: gene ? Length: 144764  
Location: 2:25733753-25878516 reverse strand Cyto location: 2p23.3


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

163 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

90 Rna Seq Results