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Gene : FBXL8 Homo sapiens

Name  ? F-box and leucine rich repeat protein 8 Cytological Location  16q22.1
Brief Description  F-box and leucine rich repeat protein 8
description  This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc002erk.2,
  • Fbl8,
  • HGNC:17875,
  • OTTHUMG00000137514,
  • NM_018378,
  • AK002140,
  • FBXL8,
  • FBL8
  • identifiers:
  • 55336,
  • ENSG00000135722,
  • FBXL8

Genome feature

Region: gene ? Length: 4187  
Location: 16:67159988-67164174 Cyto location: 16q22.1


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

73 SN Ps

5 Cross References

14 Data Sets

10 Homologues

0 Located Features

90 Rna Seq Results