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Gene : PIDD1 Homo sapiens

Name  ? p53-induced death domain protein 1 Cytological Location  11p15.5
Brief Description  p53-induced death domain protein 1
description  The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
  • synonyms:
  • PIDD1,
  • MGC16925,
  • leucine-rich repeats and death domain containing,
  • DKFZp434D229,
  • LRDD,
  • AF229178,
  • NM_145886,
  • p53-induced death domain protein,
  • OTTHUMG00000133306,
  • PIDD,
  • HGNC:16491,
  • PIDD,
  • LRDD
  • identifiers:
  • 55367,
  • ENSG00000177595,
  • PIDD1

Genome feature

Region: gene ? Length: 10689  
Location: 11:799179-809867 reverse strand Cyto location: 11p15.5

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0 Diseases

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2011 SN Ps

5 Cross References

17 Data Sets

30 Homologues

0 Located Features

90 Rna Seq Results