help  | about  | cite  | software

Gene : PPY Homo sapiens

Name  ? pancreatic polypeptide Cytological Location  17q21.31
Brief Description  pancreatic polypeptide
description  This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
  • synonyms:
  • PPY,
  • HGNC:9327,
  • OTTHUMG00000181800,
  • prepro-PP (prepropancreatic polypeptide),
  • PNP,
  • PNP,
  • pancreatic polypeptide Y,
  • PP,
  • NM_002722,
  • uc002iep.4
  • identifiers:
  • 5539,
  • ENSG00000108849,
  • PPY

Genome feature

Region: gene ? Length: 3411  
Location: 17:43940802-43944212 reverse strand Cyto location: 17q21.31


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

3 SN Ps

4 Cross References

14 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results