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Gene : EXOC2 Homo sapiens

Name  ? exocyst complex component 2 Cytological Location  6p25.3
Brief Description  exocyst complex component 2
description  The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
  • synonyms:
  • SEC5L1,
  • AJ420556,
  • SEC5,
  • Sec5p,
  • SEC5L1,
  • uc003mtd.5,
  • NM_018303,
  • HGNC:24968,
  • Sec5p,
  • EXOC2,
  • FLJ11026,
  • SEC5-like 1 (S. cerevisiae),
  • OTTHUMG00000137437
  • identifiers:
  • 55770,
  • ENSG00000112685,
  • EXOC2

Genome feature

Region: gene ? Length: 208004  
Location: 6:485138-693141 reverse strand Cyto location: 6p25.3

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2011 SN Ps

5 Cross References

16 Data Sets

6 Homologues

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90 Rna Seq Results