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Gene : PCDHGA10 Homo sapiens

Name  ? protocadherin gamma subfamily A, 10 Cytological Location  5q31.3
Brief Description  protocadherin gamma subfamily A, 10
description  This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
  • synonyms:
  • PCDHGA10,
  • PCDH-GAMMA-A10,
  • uc003lkl.3,
  • HGNC:8697,
  • PCDH-GAMMA-A10,
  • NM_018913,
  • OTTHUMG00000163688
  • identifiers:
  • 56106,
  • ENSG00000253846,
  • PCDHGA10

Genome feature

Region: gene ? Length: 99804  
Location: 5:141413176-141512979 Cyto location: 5q31.3


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0 Pathways

57 SN Ps

4 Cross References

12 Data Sets

90 Homologues

0 Located Features

90 Rna Seq Results