help  | about  | cite  | software

Gene : PRRG1 Homo sapiens

Name  ? proline rich and Gla domain 1 Cytological Location  Xp21.1
Brief Description  proline rich and Gla domain 1
description  This gene encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]
  • synonyms:
  • uc004ddo.3,
  • OTTHUMG00000021360,
  • PRRG1,
  • proline-rich Gla (G-carboxyglutamic acid) polypeptide 1,
  • NM_000950,
  • PRGP1,
  • PRGP1,
  • HGNC:9469,
  • AF009242
  • identifiers:
  • 5638,
  • ENSG00000130962,
  • PRRG1

Genome feature

Region: gene ? Length: 108021  
Location: X:37349275-37457295 Cyto location: Xp21.1

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

36 SN Ps

5 Cross References

14 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results