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Gene : PRSS8 Homo sapiens

Name  ? serine protease 8 Cytological Location  16p11.2
Brief Description  serine protease 8
description  This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation. [provided by RefSeq, Feb 2016]
  • synonyms:
  • protease, serine 8,
  • PRSS8,
  • OTTHUMG00000176750,
  • prostasin,
  • U33446,
  • NM_002773,
  • uc002ebc.5,
  • CAP1,
  • HGNC:9491
  • identifiers:
  • 5652,
  • ENSG00000052344,
  • PRSS8

Genome feature

Region: gene ? Length: 4330  
Location: 16:31131433-31135762 reverse strand Cyto location: 16p11.2

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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110 SN Ps

5 Cross References

15 Data Sets

32 Homologues

0 Located Features

90 Rna Seq Results