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Gene : PSMD11 Homo sapiens

Name  ? proteasome 26S subunit, non-ATPase 11 Cytological Location  17q11.2
Brief Description  proteasome 26S subunit, non-ATPase 11
description  The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
  • synonyms:
  • uc002hhm.5,
  • AB003102,
  • OTTHUMG00000132811,
  • p44.5,
  • NM_002815,
  • S9,
  • p44.5,
  • Rpn6,
  • HGNC:9556,
  • S9,
  • MGC3844,
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 11,
  • PSMD11,
  • Rpn6
  • identifiers:
  • 5717,
  • ENSG00000108671,
  • PSMD11

Genome feature

Region: gene ? Length: 38857  
Location: 17:32444463-32483319 Cyto location: 17q11.2


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148 Pathways

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148 Pathways

175 SN Ps

5 Cross References

18 Data Sets

9 Homologues

0 Located Features

90 Rna Seq Results