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Gene : PVT1 Homo sapiens

Name  ? Pvt1 oncogene Cytological Location  8q24.21
Brief Description  Pvt1 oncogene (non-protein coding)
description  This gene represents a long non-coding RNA locus that has been identified as a candidate oncogene. Increased copy number and overexpression of this gene are associated with many types of cancers including breast and ovarian cancers, acute myeloid leukemia and Hodgkin lymphoma. Allelic variants of this gene are also associated with end-stage renal disease attributed to type 1 diabetes. Consistent with its association with various types of cancer, transcription of this gene is regulated by the tumor suppressor p53 through a canonical p53-binding site, and it has been implicated in regulating levels of the proto-oncogene MYC to promote tumorigenesis. [provided by RefSeq, Sep 2015]
  • synonyms:
  • MIR1204HG,
  • Pvt1 oncogene (non-protein coding),
  • HGNC:9709,
  • long intergenic non-protein coding RNA 79,
  • Pvt1 oncogene homolog (mouse),
  • PVT1,
  • LINC00079,
  • onco-lncRNA-100,
  • pvt-1 (murine) oncogene homolog, MYC activator,
  • LINC00079,
  • M31519,
  • uc003ysl.4,
  • MIR1204, MIR1205, MIR1206 and MIR1207 host gene,
  • MIR1204HG,
  • non-protein coding RNA 79,
  • OTTHUMG00000164871,
  • NCRNA00079,
  • onco-lncRNA-100,
  • NR_003367,
  • NCRNA00079
  • identifiers:
  • 5820,
  • ENSG00000249859,
  • PVT1

Genome feature

Region: gene ? Length: 306721  
Location: 8:127794533-128101253 Cyto location: 8q24.21

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0 Pathways

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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0 Pathways

518 SN Ps

5 Cross References

11 Data Sets

0 Homologues

0 Located Features

53 Rna Seq Results