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Gene : NECAB3 Homo sapiens

Name  ? N-terminal EF-hand calcium binding protein 3 Cytological Location  20q11.22
Brief Description  N-terminal EF-hand calcium binding protein 3
description  The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • EFCBP3,
  • OTTHUMG00000032264,
  • amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein,
  • STIP3,
  • APBA2BP,
  • uc002wzn.5,
  • dJ63M2.5,
  • SYTIP2,
  • XB51,
  • NIP1,
  • EFCBP3,
  • NM_031231,
  • AB039947,
  • EF-hand calcium binding protein 3,
  • dJ63M2.4,
  • HGNC:15851,
  • dJ63M2.5,
  • SYTIP2,
  • NIP1,
  • NECAB3,
  • APBA2BP,
  • dJ63M2.4,
  • XB51
  • identifiers:
  • 63941,
  • ENSG00000125967,
  • NECAB3

Genome feature

Region: gene ? Length: 17372  
Location: 20:33657087-33674458 reverse strand Cyto location: 20q11.22


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0 Pathways

177 SN Ps

5 Cross References

15 Data Sets

4 Homologues

0 Located Features

90 Rna Seq Results