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Gene : P2RY12 Homo sapiens

Name  ? purinergic receptor P2Y12 Cytological Location  3q25.1
Brief Description  purinergic receptor P2Y12
description  The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  • synonyms:
  • purinergic receptor P2Y, G-protein coupled, 12,
  • P2Y(ADP),
  • P2Y(12)R,
  • P2Y(cyc),
  • uc003eyx.3,
  • HORK3,
  • P2RY12,
  • NM_022788,
  • AJ320495,
  • P2Y12,
  • P2Y12,
  • P2T(AC),
  • SP1999,
  • HORK3,
  • P2Y(AC),
  • ADPG-R,
  • HGNC:18124,
  • OTTHUMG00000159863,
  • BDPLT8,
  • SP1999
  • identifiers:
  • 64805,
  • ENSG00000169313,
  • P2RY12

Genome feature

Region: gene ? Length: 47970  
Location: 3:151336843-151384812 reverse strand Cyto location: 3q25.1


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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

2011 SN Ps

5 Cross References

17 Data Sets

9 Homologues

0 Located Features

90 Rna Seq Results