help  | about  | cite  | software

Gene : SKIL Homo sapiens

Name  ? SKI like proto-oncogene Cytological Location  3q26.2
Brief Description  SKI like proto-oncogene
description  The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
  • synonyms:
  • SnoN,
  • NM_005414,
  • uc003fgw.4,
  • X15217,
  • SnoA,
  • OTTHUMG00000158831,
  • SKI-like oncogene,
  • SNO,
  • SnoI,
  • SnoA,
  • SKIL,
  • SNO,
  • SnoN,
  • HGNC:10897
  • identifiers:
  • 6498,
  • ENSG00000136603,
  • SKIL

Genome feature

Region: gene ? Length: 39172  
Location: 3:170357678-170396849 Cyto location: 3q26.2


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

170 SN Ps

5 Cross References

17 Data Sets

8 Homologues

0 Located Features

90 Rna Seq Results