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Gene : TARBP2 Homo sapiens

Name  ? TARBP2 subunit of RISC loading complex Cytological Location  12q13.13
Brief Description  TARBP2, RISC loading complex RNA binding subunit
description  HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc001sdo.4,
  • LOQS,
  • NM_004178,
  • TARBP2,
  • OTTHUMG00000169855,
  • TRBP,
  • TRBP2,
  • TARBP2, RISC loading complex RNA binding subunit,
  • TRBP1,
  • HGNC:11569,
  • Trbp,
  • TAR (HIV-1) RNA binding protein 2
  • identifiers:
  • 6895,
  • ENSG00000139546,
  • TARBP2

Genome feature

Region: gene ? Length: 5511  
Location: 12:53500921-53506431 Cyto location: 12q13.13

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0 Diseases

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384 SN Ps

5 Cross References

15 Data Sets

7 Homologues

0 Located Features

90 Rna Seq Results