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Gene : TLE3 Homo sapiens

Name  ? TLE family member 3, transcriptional corepressor Cytological Location  15q23
Brief Description  transducin like enhancer of split 3
description  This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]
  • synonyms:
  • HsT18976,
  • ESG,
  • transducin like enhancer of split 3,
  • ESG3,
  • ESG,
  • OTTHUMG00000172121,
  • HGNC:11839,
  • GRG3,
  • KIAA1547,
  • M99438,
  • HsT18976,
  • GRG3,
  • NM_005078,
  • transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila),
  • ESG3,
  • uc002asm.4,
  • TLE3
  • identifiers:
  • 7090,
  • ENSG00000140332,
  • TLE3

Genome feature

Region: gene ? Length: 50382  
Location: 15:70047790-70098171 reverse strand Cyto location: 15q23

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0 Diseases

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15 SN Ps

5 Cross References

16 Data Sets

11 Homologues

0 Located Features

90 Rna Seq Results