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Gene : TSPAN6 Homo sapiens

Name  ? tetraspanin 6 Cytological Location  Xq22.1
Brief Description  tetraspanin 6
description  The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013]
  • synonyms:
  • uc004ega.3,
  • TM4SF6,
  • TSPAN-6,
  • HGNC:11858,
  • transmembrane 4 superfamily member 6,
  • TSPAN-6,
  • TM4SF6,
  • T245,
  • T245,
  • AF043906,
  • TSPAN6,
  • NM_001278740,
  • OTTHUMG00000022002
  • identifiers:
  • 7105,
  • ENSG00000000003,
  • TSPAN6

Genome feature

Region: gene ? Length: 9997  
Location: X:100627108-100637104 reverse strand Cyto location: Xq22.1

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0 Pathways

Gene --> GO terms.

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Mouse Gene --> Allele [Phenotype]


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Gene --> Orthologues


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

679 SN Ps

5 Cross References

15 Data Sets

35 Homologues

0 Located Features

90 Rna Seq Results