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Gene : PAX8 Homo sapiens

Name  ? paired box 8 Cytological Location  2q14.1
Brief Description  paired box 8
description  This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
  • synonyms:
  • NM_003466,
  • uc010yxt.3,
  • PAX8,
  • paired box gene 8,
  • OTTHUMG00000128529,
  • X69699,
  • HGNC:8622
  • identifiers:
  • 7849,
  • ENSG00000125618,
  • PAX8

Genome feature

Region: gene ? Length: 62925  
Location: 2:113215997-113278921 reverse strand Cyto location: 2q14.1


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Function

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Genomics

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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Homology

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Interactions

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Expression

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Other

2011 SN Ps

5 Cross References

19 Data Sets

12 Homologues

0 Located Features

90 Rna Seq Results