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Gene : FTO Homo sapiens

Name  ? FTO alpha-ketoglutarate dependent dioxygenase Cytological Location  16q12.2
Brief Description  FTO, alpha-ketoglutarate dependent dioxygenase
description  This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
  • synonyms:
  • NM_001080432,
  • HGNC:24678,
  • KIAA1752,
  • FTO,
  • uc002ehr.4,
  • BC003583,
  • MGC5149,
  • ALKBH9,
  • alpha-ketoglutarate-dependent dioxygenase,
  • fat mass and obesity associated,
  • GDFD,
  • alkB homolog 9,
  • BMIQ14,
  • ALKBH9,
  • OTTHUMG00000158780,
  • FTO, alpha-ketoglutarate dependent dioxygenase
  • identifiers:
  • 79068,
  • ENSG00000140718,
  • FTO

Genome feature

Region: gene ? Length: 410505  
Location: 16:53703963-54114467 Cyto location: 16q12.2


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Disease

2 Diseases

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Other

421 SN Ps

5 Cross References

19 Data Sets

3 Homologues

0 Located Features

90 Rna Seq Results