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Gene : ADAM12 Homo sapiens

Name  ? ADAM metallopeptidase domain 12 Cytological Location  10q26.2
Brief Description  ADAM metallopeptidase domain 12
description  This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. [provided by RefSeq, Jan 2014]
  • synonyms:
  • MLTNA,
  • MLTN,
  • uc001ljk.4,
  • AF023476,
  • ADAM12-OT1,
  • MCMPMltna,
  • CAR10,
  • MCMPMltna,
  • MLTN,
  • ADAM12,
  • NM_001288973,
  • meltrin alpha,
  • MCMP,
  • a disintegrin and metalloproteinase domain 12 (meltrin alpha),
  • HGNC:190,
  • OTTHUMG00000019243
  • identifiers:
  • 8038,
  • ENSG00000148848,
  • ADAM12

Genome feature

Region: gene ? Length: 376174  
Location: 10:126012385-126388558 reverse strand Cyto location: 10q26.2


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

106 SN Ps

5 Cross References

17 Data Sets

28 Homologues

0 Located Features

90 Rna Seq Results