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Gene : ADAMTS12 Homo sapiens

Name  ? ADAM metallopeptidase with thrombospondin type 1 motif 12 Cytological Location  5p13.3-p13.2
Brief Description  ADAM metallopeptidase with thrombospondin type 1 motif 12
description  This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion. [provided by RefSeq, Jul 2008]
  • synonyms:
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12,
  • AJ250725,
  • HGNC:14605,
  • PRO4389,
  • OTTHUMG00000162088,
  • uc003jia.3,
  • NM_030955,
  • ADAMTS12
  • identifiers:
  • 81792,
  • ENSG00000151388,
  • ADAMTS12

Genome feature

Region: gene ? Length: 368658  
Location: 5:33523535-33892192 reverse strand Cyto location: 5p13.3-p13.2


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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

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Other

365 SN Ps

5 Cross References

14 Data Sets

30 Homologues

0 Located Features

90 Rna Seq Results