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Gene : ADAMTS10 Homo sapiens

Name  ? ADAM metallopeptidase with thrombospondin type 1 motif 10 Cytological Location  19p13.2
Brief Description  ADAM metallopeptidase with thrombospondin type 1 motif 10
description  This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_030957,
  • uc002mkj.3,
  • a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 10,
  • WMS1,
  • ADAMTS-10,
  • WMS,
  • ADAM-TS10,
  • AF163762,
  • HGNC:13201,
  • ADAM-TS10,
  • OTTHUMG00000182216,
  • ADAMTS10
  • identifiers:
  • 81794,
  • ENSG00000142303,
  • ADAMTS10

Genome feature

Region: gene ? Length: 30496  
Location: 19:8580240-8610735 reverse strand Cyto location: 19p13.2


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

58 SN Ps

5 Cross References

18 Data Sets

31 Homologues

0 Located Features

90 Rna Seq Results