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Gene : PLA2G12B Homo sapiens

Name  ? phospholipase A2 group XIIB Cytological Location  10q22.1
Brief Description  phospholipase A2 group XIIB
description  The protein encoded by this gene belongs to the phospholipase A2 (PLA2) group of enzymes, which function in glycolipid hydrolysis with the release of free fatty acids and lysophospholipids. This family member has altered phospholipid-binding properties and is catalytically inactive. The protein is secreted, and together with microsomal triglyceride transfer protein, it functions to regulate HNF4alpha-induced hepatitis C virus infectivity. The expression of this gene is down-regulated in various tumors, suggesting that it may function as a negative regulator of tumor progression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]
  • synonyms:
  • NM_032562,
  • OTTHUMG00000018446,
  • PLA2G13,
  • PLA2G13,
  • phospholipase A2, group XIIB,
  • phospholipase A2, group XIII,
  • PLA2G12B,
  • FKSG71,
  • HGNC:18555,
  • AF349540,
  • sPLA2-GXIIB,
  • uc001jtf.2,
  • identifiers:
  • 84647,
  • ENSG00000138308,
  • PLA2G12B

Genome feature

Region: gene ? Length: 20283  
Location: 10:72934762-72955044 reverse strand Cyto location: 10q22.1

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0 Diseases

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4 SN Ps

5 Cross References

15 Data Sets

8 Homologues

0 Located Features

90 Rna Seq Results