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Gene : CNTNAP1 Homo sapiens

Name  ? contactin associated protein 1 Cytological Location  17q21.2
Brief Description  contactin associated protein 1
description  The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq, Jan 2009]
  • synonyms:
  • OTTHUMG00000180643,
  • CHN3,
  • CNTNAP,
  • P190,
  • U87223,
  • Caspr,
  • p190,
  • HGNC:8011,
  • CNTNAP1,
  • uc002iay.4,
  • neurexin 4,
  • CNTNAP,
  • CASPR,
  • NRXN4,
  • NRXN4,
  • NM_003632
  • identifiers:
  • 8506,
  • ENSG00000108797,
  • CNTNAP1

Genome feature

Region: gene ? Length: 20227  
Location: 17:42679767-42699993 Cyto location: 17q21.2


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2 Diseases

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2011 SN Ps

5 Cross References

19 Data Sets

16 Homologues

0 Located Features

90 Rna Seq Results